Gian Pietro Miscione

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Gian Pietro Miscione

Gian Pietro Miscione

Doctor en Ciencias - Químicas

gp.miscione57 @uniandes.edu.co

Profesor Asociado

Extension: 2788

Departamento de Química

Profile
Courses
Products
Degrees
Projects

Profile

Recent Courses

  • 2021
    • QUÍMICA COMPUTACIONAL

      First period
      Bachelor Level

      QUÍMICA

      First period
      Bachelor Level

Recent Products

Elejalde N, García-Olave Mayra, Figueroa D, Vidossich P, Miscione G, Portilla J. (2022)
Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles
Molecules (ISSN 1420-3049)
Article
Ballesteros A, Vidossich P, Melo C, Jiménez E, Castillo J, Portilla J, Miscione G. (2022)
Synthesis of 2,7-diarylpyrazolo [1,5-a] pyrimidine derivatives with antitumor activity. Theoretical identification of targets
European Journal of Medicinal Chemistry Reports (ISSN 2772-4174)
Article

Recent Degrees

Doctor en Ciencias - Químicas

Doctoral degree

Universitá Degli Studi Di Bologna

2001

Italia

Magíster en Química

Master degree

Universitá Degli Studi Di Bologna

1996

Italia

Recent Projects

  • 2015
    • Estudio computacional de procesos orgánicos y bioquímicos

      Duration: 36 months

      PR.3.2015.2535

Courses

  • 2021
    • QUÍMICA COMPUTACIONAL

      First period
      Bachelor Level

      QUÍMICA

      First period
      Bachelor Level
    • CUÁNTICA Y COMPUTACIONAL AVANZ

      First period
      Master Level
  • 2020
    • QUÍMICA COMPUTACIONAL

      First period
      Bachelor Level

      BIOINFORMATICA

      Second period
      Master Level
    • FUNDAMENTOS DE FISICOQUÍMICA

      First period
      Bachelor Level

      QUÍMICA

      Second period
      Bachelor Level
    • CUÁNTICA Y COMPUTACIONAL AVANZ

      First period
      Master Level

      FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level
  • 2019
    • QUÍMICA

      First period
      Bachelor Level

      CUÁNTICA Y COMPUTACIONAL AVANZ

      First period
      Master Level
    • QUIMICA COMPUTACIONAL

      First period
      Bachelor Level

      FUNDAMENTOS DE FISICOQUÍMICA

      First period
      Bachelor Level
    • SEMINARIO I

      First period
      Master Level

      QUIMICA GENERAL

      Second period
      Bachelor Level
    • FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level

      BIOINFORMATICA

      Second period
      Master Level
    • SEMINARIO I

      Second period
      Master Level
  • 2018
    • QUIMICA COMPUTACIONAL

      First period
      Bachelor Level

      FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level
    • SEMINARIO I

      Second period
      Master Level

      FUNDAMENTOS DE FISICOQUÍMICA

      First period
      Bachelor Level
    • CUÁNTICA Y COMPUTACIONAL AVANZ

      First period
      Master Level

      QUÍMICA

      Second period
      Bachelor Level
  • 2017
    • QUÍMICA ORGÁNICA I

      First period
      Bachelor Level

      FUNDAMENTOS DE FISICOQUÍMICA

      First period
      Bachelor Level
    • QUIMICA GENERAL

      First period
      Bachelor Level

      QUIMICA GENERAL

      Second period
      Bachelor Level
    • FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level

      QUIMICA COMPUTACIONAL

      First period
      Bachelor Level
    • BIOINFORMATICA

      Second period
      Master Level
  • 2016
    • APLICACIONES DE QUÍMICA

      First period
      Bachelor Level

      QUÍMICA ORGÁNICA I

      First period
      Bachelor Level
    • APLICACIONES DE QUÍMICA

      Second period
      Bachelor Level

      INTRODUCCION A LA QUIMICA

      Second period
      Bachelor Level
    • QUIMICA GENERAL

      Second period
      Bachelor Level

      QUÍMICA

      Second period
      Bachelor Level
    • FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level

      FUNDAMENTOS QUÍMICA ORGÁNICA

      Second period
      Bachelor Level
  • 2015
    • QUIMICA GENERAL

      First period
      Bachelor Level

      SEMINARIO AVANZADO

      Second period
      Bachelor Level
    • APLICACIONES DE QUÍMICA

      First period
      Bachelor Level

      APLICACIONES DE QUÍMICA

      Second period
      Bachelor Level
    • FUNDAMENTOS DE FISICOQUÍMICA

      First period
      Bachelor Level
  • 2014
    • QUIMICA GENERAL

      Second period
      Bachelor Level

      FUNDAMENTOS DE FISICOQUÍMICA

      Second period
      Bachelor Level

Products

Elejalde N, García-Olave Mayra, Figueroa D, Vidossich P, Miscione G, Portilla J. (2022)
Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles
Molecules (ISSN 1420-3049)
Article
Ballesteros A, Vidossich P, Melo C, Jiménez E, Castillo J, Portilla J, Miscione G. (2022)
Synthesis of 2,7-diarylpyrazolo [1,5-a] pyrimidine derivatives with antitumor activity. Theoretical identification of targets
European Journal of Medicinal Chemistry Reports (ISSN 2772-4174)
Article
Mestizo P, Narváez DM, Pinzon J, Torres D, Franco S, Mario A. Macías, Groot H, Miscione G, Suescun L, Hurtado J. (2021)
Novel complexes with ONNO tetradentate coumarin schiff-base donor ligands: x-ray structures, DFT calculations, molecular dynamics and potential anticarcinogenic activity
Biometals (ISSN 0966-0844)
Article
Miscione G, Vidossich P, De Vivo M, Castañeda L, Mota Cristiano, Daniele De Sanctis. (2020)
Functional Implications of Second-shell Basic Residues for dUTPase DR2231 Enzymatic Specificity
ACS Catalysis (ISSN 2155-5435)
Article
Prada C .(2020). VeBaMoS: un código de similaridad molecular basado en vectores : manual de usuario.
VeBaMoS: un código de similaridad molecular basado en vectores : manual de usuario
Thesis
Miscione G.
A double M, please! The story of Maud Menten
Event
Mario A. Macías, Torres J, Franco S, Miscione G, Hurtado J.
Crystal Structure of Cu(II) and Zn(II) Complexes with Dinitrobenzoates and Pyrazolyl Ligands. Thermal Stability and Influence of N-H Moiety
Event
Torres J, Mario A. Macías, Franco S, Miscione G, Cobo J, Hurtado J. (2019)
Cu(II) and Zn(II) Complexes with Dinitrobenzoates and Pyrazolyl Lig-ands: Structural and Thermal Stability Influence of N-H Moiety
Crystal Growth & Design (ISSN 1528-7483)
Article
Melendez D .(2018). Aislamiento y estudio computacional de alcaloides en Lycopodium thyoides como posibles inhibidores de la enzima acetilcolinesterasa para el tratamiento de la enfermedad de Alzheimer.
Aislamiento y estudio computacional de alcaloides en Lycopodium thyoides como posibles inhibidores de la enzima acetilcolinesterasa para el tratamiento de la enfermedad de Alzheimer
Thesis
Becerra L, Gamba D, Miscione G, S.Movilla. (2018)
An intramolecular oxa-Michael reaction on α,β-unsaturated α-amino-δ-hydroxycarboxylic acid esters. Synthesis of functionalized 1,3-dioxanes
Organic and Biomolecular Chemistry (ISSN 1477-0520)
Article
Ruiz M .(2018). Búsqueda computacional de inhibidores de la bomba de expulsión MtrCDE de Neisseria gonorrhoeae.
Búsqueda computacional de inhibidores de la bomba de expulsión MtrCDE de Neisseria gonorrhoeae
Thesis
Miscione G, A Bottoni, Bandini M. (2018)
Covalent or Non-Covalent? A Mechanistic Insight into the Enantioselective BrØnsted Acid Catalyzed Dearomatization of Indoles with Allenamides
Chem Cat Chem (ISSN 1867-3880)
Article
Castañeda L .(2018). ESTUDIO COMPUTACIONAL DEL MECANISMO DE REACCIÓN DE LA ENZIMA DR2231 DE Deinococus radiodurans.
ESTUDIO COMPUTACIONAL DEL MECANISMO DE REACCIÓN DE LA ENZIMA DR2231 DE Deinococus radiodurans
Thesis
Miscione G. (2018)
En búsqueda de blancos moleculares
Química E Industria (ISSN 0370-2871)
Article
Hurtado J .(2018). Estudio computacional dirigido al diseño de análogos de antimicina como potenciales inhibidores de la AGPS.
Estudio computacional dirigido al diseño de análogos de antimicina como potenciales inhibidores de la AGPS
Thesis
Miscione G.
Exploring uncharted territories with computational chemistry
Event
Miscione G. (2018)
La ciencia y la guerra: la historia del químico Fritz Haber
Revista Arcadia (ISSN 1900-589x)
Article
Miscione G. (2018)
La pila
Journalistic Production
Miscione G.
Las nuevas fronteras de la química computacional
Event
Miscione G.
Mechanism of L-Tryptophan Prenylation, Catalyzed by FgaPT2: a Computational Study
Event
Miscione G, Franco S, De Vivo M, La Sala G. (2018)
Novel Bacterial Topoisomerase Inhibitors Exploit Asp83 and the Intrinsic Flexibility of the DNA Gyrase Binding Site
International Journal of Molecular Sciences (ISSN 1422-0067)
Article
Posada A, Mario A. Macías, Miscione G, S.Movilla, Hurtado J. (2018)
Polymers of ε-Caprolactone Using New Copper(II) and Zinc(II) Complexes as Initiators. Synthesis, Characterization and X-ray Crystal Structures
Polymers (ISSN 2073-4360)
Article
Correal S .(2018). Transferencia de Acilo de N a O: un Estudio Computacional.
Transferencia de Acilo de N a O: un Estudio Computacional
Thesis
Miscione G.
1st Protein Structure, Function and Drug Discovery School
Event
Hurtado J, Nuñez-Dallos N, S.Movilla, Miscione G, People B, Rojas R, Valderrama M, Fröhlich R. (2017)
Chromium(III) complexes bearing bis(benzotriazolyl)pyridine ligands: synthesis, characterization and ethylene polymerization behavior
Journal of Coordination Chemistry (ISSN 0095-8972)
Article
Miscione G.
Docking molecular: el papel de la química computacional en la búsqueda de fármacos
Event
Solano A .(2017). Estudio computacional de la polimerización de epsilon - caprolactona catalizada / iniciada por derivados de bis(dimetilpirazol)Cu(II) y Zn(II).
Estudio computacional de la polimerización de epsilon - caprolactona catalizada / iniciada por derivados de bis(dimetilpirazol)Cu(II) y Zn(II)
Thesis
Zuñiga D .(2017). Estudio teórico de las transiciones fotofísicas entre estados singlete y triplete del contaminante atmosférico peróxido de cloro.
Estudio teórico de las transiciones fotofísicas entre estados singlete y triplete del contaminante atmosférico peróxido de cloro
Thesis
Miscione G.
Frankenstein, Nuevas Miradas Políticas Y Estéticas
Event
Bandini M, Cera G, Miscione G. (2017)
Unveiling the Reaction Machinery of the [AuI]-Catalyzed Synthesis of Substituted Acenes by a [1,5]-H Shift Cascade Reaction
Chem Cat Chem (ISSN 1867-3880)
Article
Miscione G. (2017)
Unveiling the reaction machinery of the [Au(I)]-catalyzed synthesis of substituted acenes via [1,5]-H shift cascade reaction
Article
Miscione G, A Bottoni. (2016)
A mechanistic insights into manganese-catalyzed oxidative homocoupling reactions of Grignard reagents: A computational DFT investigation
Journal of Organometallic Chemistry (ISSN 0022-328X)
Article
Franco S .(2016). Application of Molecular Mechanics for the Discovery of Novel Microbial IIA Topoisomerases Inhibitors.
Application of Molecular Mechanics for the Discovery of Novel Microbial IIA Topoisomerases Inhibitors
Thesis
Ramos C .(2016). ESTUDIO DE VIRTUAL SCREENING Y SIMULACIONES DE DINA?MICA MOLECULAR APLICADAS EN EL DISEN?O DE POTENTES Y SELECTIVOS INHIBIDORES DE LA ENZIMA CASPASA-1 HACIA LA ENFERMEDAD DE ALZHEIMER.
ESTUDIO DE VIRTUAL SCREENING Y SIMULACIONES DE DINA?MICA MOLECULAR APLICADAS EN EL DISEN?O DE POTENTES Y SELECTIVOS INHIBIDORES DE LA ENZIMA CASPASA-1 HACIA LA ENFERMEDAD DE ALZHEIMER
Thesis
Miscione G, Franco S, Ramos C. (2016)
Jugando a ser Dios: la evolución del diseño de medicamentos y el rol de los métodos computacionales
Hipótesis: Apuntes Científicos Uniandinos (ISSN 1692-729X)
Article
Miscione G. (2016)
Laura Bassi: de los Apeninos a los Andes
Hipótesis: Apuntes Científicos Uniandinos (ISSN 1692-729X)
Article
Miscione G, Giacinto P, Cera G, Bottoni A, Bandini M. (2015)
A DFT mechanistic investigation of the gold(I) catalyzed synthesis of azepino[1,2-a]indoles
Chem Cat Chem (ISSN 1867-3880)
Article
Miscione G, Ocello R, De A, Jia M, Yang Q, Giacinto P, Bottoni A, Bandini M. (2015)
Gold(I)-dearomative [2+2]-Cycloaddition of Indoles with Activated Allenes. A Combined Experimental Computational Study
Chemistry A European Journal (ISSN 1521-3765)
Article
Valencia A, Miscione G. (2015)
La luz: color y mucho más
Hipótesis: Apuntes Científicos Uniandinos (ISSN 1692-729X)
Article
Miscione G. (2015)
Las ranas de Galvani, la pila de Volta y el sueño del doctor Frankenstein
Hipótesis: Apuntes Científicos Uniandinos (ISSN 1692-729X)
Article
Miscione G.
Las ranas de Galvani, la pila de Volta y el sueño del doctor Frankenstein
Event
Miscione G, Mastandrea M, Mellonei N, Giacinto P, Collado A, Nolan S, Bottoni A, Bandini M. (2015)
[Au(I)]-assisted alpha Allylation of Enals and Enones with Alcohols
Angewandte Chemie International Edition ()
Article
Miscione G, Bottoni A. (2014)
C−CN vs C−H Activation: Actual Mechanism of the Reaction between [(dippe)PtH]2 and Benzonitrile Evidenced by a DFT Computational Investigation
Organometallics (ISSN 0276-7333)
Article
Miscione G, Tajes M, Eraso A, Rubio F, Guivernau B, Ramos E, Bosch M, Xavier F, Clarimon J, Boada M, Suzuki T, Molina H, Villa J, Vicente R, Muñoz F. (2014)
Methylglyoxal Produced by Amyloid -Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer Disease
Journal of Alzheimer's Disease (ISSN 1387-2877)
Article
Miscione G, Bottoni A, Lombardo M, Manfroni E, Quintavalla A, Trombini C. (2013)
Electrosteric Activation Using Ion-Tagged Prolines. A Combined Experimental and Computational Investigation
Chem Cat Chem (ISSN 1867-3880)
Article
Miscione G, Bandini M, Bottoni A, Chiarucci M, Cera G. (2012)
Mechanistic Insights into Enantioselective Gold-Catalyzed Allylation of Indoles with Alcohols: the Counterion Effect
Journal of the American Chemical Society (ISSN 0002-7863)
Article
Miscione G, Bottoni A, Angels A. (2011)
Aromatic Carbon–Carbon Bond Cleavage Using Tungsten Complexes. A DFT Computational Study
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bottoni A, Calvaresi M. (2011)
Computational Evidence for the Substrate-Assisted Catalytic Mechanism of O‑GlcNAcase. A DFT Investigation
Physical Chemistry Chemical Physics (ISSN 1463-9076)
Article
Miscione G, Bottoni A, Angels A, Novoa J. (2010)
A theoretical investigation of the oxidation states of palladium complexes and their role in the carbonylation reaction
Molecular Physics (ISSN 0026-8976)
Article
Miscione G, Bandini M, Bottoni A, Eichholzer A, Stenta M. (2010)
Asymmetric Phase-Transfer-Catalyzed Intramolecular N-Alkylation of Indoles and Pyrroles: A Combined Experimental and Theoretical Investigation
Chemistry A European Journal (ISSN 1521-3765)
Article
Miscione G, Calvaresi M, Bottoni A. (2010)
Computational Evidence for the Catalytic Mechanism of Caspase-7. A DFT Investigation
Journal of Physical Chemistry B (ISSN 1520-6106)
Article
Miscione G, Xavier F, Ill G, Bravo R, Nakaya T, De-fabritiis G, Coma M, Villà J, Suzuki T, Fernàndez X, Valverde M, De B, Muñoz F. (2009)
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation
Brain (ISSN 0006-8950)
Article
Miscione G, Bottoni A, Trombini C, Lombardo M, Pujol J. (2008)
3-Bromozinc Propenyl Esters: an Experimental and Theoretical Study of the Unique Stereocrossover Observed in their Addition to Aromatic and Aliphatic Aldehydes
Journal of Organic Chemistry (ISSN 0022-3263)
Article
Miscione G, Torroni S, Innorta G, Bottoni A. (2007)
Mechanism of the gas phase reactions of the C5H5Ni+ and C5H5Co+ ions with substituted pyridines. A combined experimental and theoretical study
Inorganica Chimica Acta (ISSN 0020-1693)
Article
Miscione G, Stenta M, Spinelli D, Anders E, Bottoni A. (2007)
New computational evidence for the catalytic mechanism of carbonic anhydrase
Theoretical Chemistry Accounts (ISSN 1432-2234)
Article
Miscione G, Carvajal M, Accardi A, Novoa J, Bottoni A. (2006)
A DFT Computational Study of the Mechanism of Butadiene Carbonylation Catalyzed by Palladium Complexes
Molecular Physics (ISSN 0026-8976)
Article
Miscione G, Bandini M, Bottoni A, Cozzi P, Monari M, Pierciaccante R, Umani A. (2006)
Chiral Boron C2-Bis(oxazolines) in Asymmetric Catalysis. A Theoretical Study of the Catalyzed Enantioselective Reduction of Ketones Promoted by Catecholborane
European Journal of Organic Chemistry (ISSN 1434-193X)
Article
Miscione G, Carvajal M, Novoa J, Bottoni A. (2006)
The Mechanism of Transition Metal Catalyzed Carbonylation of Allyl Halides. A Theoretical Investigation
Journal of Organometallic Chemistry (ISSN 0022-328X)
Article
Miscione G, Bottoni A, De M. (2005)
A Theoretical Investigation of the Lysozyme Mechanism: Computational Evidence for a Covalent Intermediate Pathway
Proteins: Structure, Function, and Bioinformatics (ISSN 1097-0134)
Article
Miscione G, Carvajal M, Novoa J, Bottoni A. (2005)
DFT Computational Study of the Mechanism of Allyl Chloride Carbonylation Catalyzed by Palladium Complexes
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bottoni A, Bonini B, Capitò E, Comes M, Ricci A, Bernardi F, Giordano L, Cowley A. (2004)
Diastereoselective Synthesis of Thieno[3,2:4,5]cyclopenta[1,d][1,3]oxazolines - New Ligands for the Copper-Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Enones
European Journal of Organic Chemistry (ISSN 1434-193X)
Article
Miscione G, Bottoni A, Lanza C, Spinelli D. (2004)
New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur?
Journal of the American Chemical Society (ISSN 0002-7863)
Article
Miscione G, Bandini M, Bernardi F, Bottoni A, Cozzi P, Umani A. (2003)
Bis(oxazoline)titanium Complexes as Chiral Catalysts for Enantioselective Hydrosilylation of Ketones - A Combined Experimental and Theoretical Investigation
European Journal of Organic Chemistry (ISSN 1434-193X)
Article
Miscione G, Bottoni A, Novoa J, Prat-resina X. (2003)
DFT Computational Study of the Mechanism of Allyl Halides Carbonylation Catalyzed by Nickel Tetracarbonyl
Journal of the American Chemical Society (ISSN 0002-7863)
Article
Miscione G, Bernardi F, Bottoni A. (2003)
DFT Study of the Olefin Metathesis Catalyzed by Ruthenium Complexes
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bottoni A, Higueruelo A. (2002)
A DFT Computational Study of the bis-Silylation Reaction of Acetylene Catalyzed by Palladium Complexes
Journal of the American Chemical Society (ISSN 0002-7863)
Article
Miscione G, Bottoni A, Bernardi F. (2002)
Applications of Density Functional Theory in the Study of Organometallic Reactivity Problems
Journal of Computational Methods in Science and Engineering (ISSN 1472-7978)
Article
Miscione G, Bernardi F, Bottoni A. (2001)
DFT Study of the Palladium-Catalyzed Cyclopropanation Reaction
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bernardi F, Bottoni A. (2000)
Metal Carbene or Carbenoid Complexes? A Theoretical Study of the Active Form of Transition Metal Catalysts in Cyclopropanation and Olefin Metathesis Reactions
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bernardi F, Bottoni A. (1998)
A Theoretical Study of the Homogeneous Ziegler-Natta Catalysis
Organometallics (ISSN 0276-7333)
Article
Miscione G, Bernardi F, Bottoni A. (1997)
A DFT Study of the Simmons-Smith Cyclopropanation Reaction
Article

Degrees

  • Doctor en Ciencias - Químicas

    Doctoral degree

    Universitá Degli Studi Di Bologna

    2001

    Italia

    Magíster en Química

    Master degree

    Universitá Degli Studi Di Bologna

    1996

    Italia

Projects

  • 2015
    • Estudio computacional de procesos orgánicos y bioquímicos

      Duration: 36 months

      PR.3.2015.2535